原发性高血压患者血压变异性与血脂的相关性研究

Correlation of Blood Pressure Variability and Lipids in Patients with Primary Hypertension

目的:探讨分析原发性高血压患者血压变异性与血脂的相关性。方法:选取本院2008年4月-2011年5月收治的80例原发性高血压伴血压变异的患者作为血压变异组,并随机选取同时期的80例单纯性原发性高血压患者作为血压无变异组,检测并对比分析两组患者的总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白、脂蛋白a及载脂蛋白。伴有血压变异的患者治疗6个月后,再次检测血脂的各项指标,并与6个月前对比分析。结果:入院检查时,原发性高血压伴血压异常的患者,其血脂要明显高于单纯性的原发性高血压患者(P<0.05),但在接受一段时间的降压及降脂治疗之后,其血压变异程度要明显低于接受治疗前(P<0.05)。结论:对于合并有血压变异的原发性高血压患者,常伴发有高血脂,将其血脂控制在正常范围内,可以明显减少血压变异。

Objective： To study the correlation of blood pressure variability and lipids in patients with primary hypertension.Method： 80 patients with primary hypertension and blood pressure variability were selected in our hospital from Apirl 2008 to May 2011 as the blood pressure variability group, 80 patients only with primary hypertension of the same period were selected as the no pressure variation group.Tbe TC, TG, HDL, LDL, LP （ A ） and Ape of all the patients were tested and analyzed, the lipids of the patients with blood pressure variability after 6 months＇ treatment, blood lipid indicators were tested and compared with 6 months ago.Result： The level of the lipids of patients with primary hypertension and blood pressure variability were obviously higher than those of the patients only with primary hypertension when the lipids were tested for the first time （ P〈0.05 ） .After 6 months＇ antihypertensive and lipid-lowering therapy, the degree of blood pressure variability of patients with.primary hypertension and blood pressure variability was obviously lower than that before the treatment （ P〈0.05 ） .Conclusion： For patients with primary hypertension and blood pressure variability, they are often combined with the hyperlipidemia.ControUing the level of lipids within the normal range can obviously reduce the variability of blood pressure.