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miRNA-29b在肿瘤中的研究进展 被引量：1

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摘要 微小RNA（miRNA）是小的非编码RNA，在转录后调控基因的表达，包括抑制蛋白的翻译或降解mRNA。miRNA可抑制或促进肿瘤的生长，其异常表达与各种肿瘤密切相关。有研究表明，miRNA在肿瘤的发生发展过程中是作为癌基因还是抑癌基因发挥作用，这取决于它们调控的靶点‘“。如有些miRNA作用于PTEN或PUMA，发挥抑癌基因的作用，而有些miRNA作用于MET，发挥癌基因的作用。miRNA一29是miRNAs家族中的一个重要组成部分，主要包括miRNA-29a、
作者 周胤余 王玉明
机构地区 昆明医科大学第一附属医院检验科
出处 《国际检验医学杂志》 CAS 2014年第4期449-452,共4页 International Journal of Laboratory Medicine
关键词 微RNA 肿瘤 综述
分类号 R730.2 [医药卫生—肿瘤]
  • 相关文献

参考文献26

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二级参考文献13

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共引文献4

同被引文献7

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国际检验医学杂志
2014年 第4期

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