长疗程治疗老年人反流性食管炎疗效观察

Effect observation of long-range treatment for elderly patients with reflux esophagitis

目的 观察长疗程治疗老年人反流性食管炎的临床疗效.方法 反流性食管炎患者124例,采用数字表法随机分为观察组62例与对照组62例,观察组予长疗程治疗（常规治疗结束后维持治疗3个月）,对照组予常规治疗,比较两组自觉症状评分、内镜下愈合情况.结果 治疗前及治疗后3个月,两组反流症状积分差异均无统计学意义（t=1.325、1.241,均P＞0.05）；治疗6个月、12个月,观察组反流症状积分明显低于对照组（t =24.325、18.124,均P＜0.01）；总疗程结束后,观察组治疗效果优良率为90.0%,高于对照组的55.7%（X^2=17.902,P＜0.01）；观察组食管炎愈合优良率为86.7%,高于对照组的57.4%（X^2=12.844,P＜0.01）.结论 长疗程治疗老年人反流性食管炎效果良好,病变愈合质量高,值得临房进一步推广.

Objective To observe the clinical effect of long-range treatment for elderly patients with reflux esophagitis.Methods 124 reflux esophagitis patients were randomly divided into observation group （62 cases） and control group （62 cases） according to random number method.The observation group received long-range treatment （maintain treatment for 3 months after the end of the routine treatment）,while the control group received conventional treatment,symptoms score and endoscopic healing of two groups were compared.Results Before treatment and 3 months after treatment,two groups of reflux symptom scores were not significantly different （t =1.325,1.241,all P 〉 0.05）,6 and 12 months after treatment,reflux symptoms score of the observation group was significantly lower than that of the control group （t =24.325,18.124,P 〈 0.01）,after total treatment,the good treatment effect rate of the observation group was 90.0%,which was higher than that of the contol group（55.7%）（x2 =17.902,P 〈0.01）,healing of esophagitis excellent rate of the observation group was 86.7%,which was higher than that of the contol group （57.4%） （X^2 =12.844,P 〈0.01）.Conclusion Long-range treatment of symptomatic improvement has good effect in elderly the reflux esophagitis,the lesion healing to improve the quality,which is worthy of further promotion research.