自拟偏瘫外洗方用于脑卒中后肢体疼痛的临床研究

Clinical study on the treatment of limbs pain of patients with depression after cerebral apoplexy with self-designed hemiparalysis-washing formula

目的探讨自拟偏瘫处洗方治疗脑卒中后肢体疼痛的临床疗效。方法收集2013年5月至2013年11月广东英德市中医院脑病科80例脑卒中后肢体疼痛患者，按随机数字表法将患者随机分为两组各40例。对照组均静滴依达拉奉注射液30mg加入0．9％氯化钠或5％葡萄糖注射液100ml中，30min内滴完，2次／d；同时配合常规偏瘫肢体功能康复训练治疗。治疗组在对照组基础上加用自拟偏瘫外洗方局部熏洗患肢，两组均治疗14d后分别观察患者疼痛视觉模拟量表（VAs）、汉密顿抑郁量表（HAMD-24）、神经功能缺损程度评分量表（MESSS）、脑卒中康复运动功能评定表（STREAM）评分情况及临床疗效。结果①临床疗效比较：治疗组治疗后总有效率为90％（36／40），对照组为70％（28／40），两组总有效率比较，差异有统计学意义（f=3．58，P〈0．01）。②两组VAS、HAMD、MESSS、STREAM评分变化比较：治疗后VAS、HAMD、MESSS、STREAM评分[治疗组分别为（2．28±0．54）分、（11．34±3．02）分、（13．49±4．27）分、（44．76±20．71）分；对照组分别为（2．90±0．75）分、（14．24±3．35）分、（17．55±4．91）分、（34．56±15．56）分]均较同组治疗前[治疗组分别为（6.21±1．27）分、（28．18±7．22）分、（26．68±7．22）分、（27．53±12．52）分；对照组分别为（6．15±1．41）分、（29．15±7．65）分、（26．56±7．65）分、（28．01±12．25）分]明显改善（P〈0．05），且治疗组疗效优于对照组（P〈0．05）。结论自拟偏瘫处洗方可改善脑卒中后患者的肢体疼痛。

Objective To study the effects of treating limbs pain of patients with depression after cerebral apoplexy with self-designed hemiparalysis-washing formula. Methods 80 patients with limbs pain after cerebral apoplexy in our hospital from May 2013 to November 2013 were recruited into a control group and a treatment group randomly, 40 patients in each group. The control group was treated with 30mg edaravone and 100rnl 0.9% sodium chloride or 0.5% glucose injection, IV in 30rain, and twice daily. Meanwhile, regular functional rehabilitation training was adopted for the patients. The treatment group was additional treated with self-designed hemiparalysis-washing formula on the basis of the control group. VAS, HAMD-24, MESSS, STREAM and therapeutic effects were evaluated in both groups after one month treatment. Results （~） clinical therapeutic effects comparison： the total effective rate was 90% and 70% in the treatment group and the control group respectively, with statistical difference between the two groups （t= 3.58, P〈0.01 ） .（Z） VAS, HAMD-24, MESSS, STREAM comparison： VAS, HAMD-24, MESSS, STREAM score was （ 2.28 ± 0.54 ）, （ 11.34 ± 3.02 ）, （ 3.4 9± 4.2 7 ） （ 44. 76±20.71 ） in the treatment group respecfivey, and （ 2.9±0. 7 5 ） （ 4.2 4 ± 3.3 5 ） （ ~ 7.5 5± 4. 91） （34.56± 15.56） in the control group respectively. Both groups showed obviously improvement than the before treatment, and the effects were better in the treatment group than the control group （all P〈0.05）. Conclusion Self-designed hemiparalysis-washing formula improve limbs pain in patients with cerebral apoplexy and relieve their depression.