补充维生素D对小囟门婴幼儿头围发育及智力测评的影响

Effect of vitamin D supplementation on small fontanels infant's growth of head circumference and Bayley intelligence test results

目的探讨婴幼儿补充维生素D对小囟门儿童头围发育及Bayley智力测评结果的关系。方法选择2010年1月-2011年11月在湖州市妇幼保健院体检的正常儿童118例作为观察对象,分为小囟门组和正常对照组,均给与维生素D,分别在月龄3、12、18个月三个时间节点测量头围值,同时在6、18个月两个时间节点做Bayley智力测试。结果小囟门组与对照组儿童在3、12、18个月头围值差异均无统计学意义(P>0.05);两组与相应年龄小儿头围正常值比较差异无统计学意义(P>0.05);两组儿童6、18个月Bayley智力测试结果均为正常。结论服用预防剂量的维生素D不会影响小囟门儿童头围的发育及智能发育,无论前囟大小均应服用预防剂量的维生素D。

Objective To observe the influence of vitamin D supplementation on small fontanel pediatric growth of head circumference and Bayley intelligence test results. Methods 118 heahhy infants aged 3months hospitalized in our Hospital from January 2010 to November 2011 were selected as the objects of the study. They were divided into two groups according to the fontanel inclined length, one was small fontanels group,the other was normal group. All infants were treated with vitamin D to prevent rickets, the head circumference of them were measured three points at 3 months, 12 months, 18 months and at 6 months, 1 8months the two points respectively Bayley intelligence test to evaluation analysis of their correla- tion. Results There were no statistically significant differences in the values of head circumference between the two groups at the age of 3 months,12 months, 18 months and the values of head circumference between the two groups and the corresponding age of pediatric were not statistically significant different. Bayley intelligence test results in two groups of the children at 6 months,18 months were normal. Conclusions Vitamin D has no adverse effect on the skull growth of chil- dren with small anterior fontanel. It is necessary to take vitamin D for rickets prevention whatever the size of anterior fontanel.