出院后早产儿特殊配方奶粉对短期生长发育的影响

Research on the short term physical development of the post-discharge-formula-fed premature infants

目的研究早产儿出院后配方奶对出院后早产儿短期生长发育的影响,为进一步制定喂养方案提供科学依据。方法采用前瞻性的成组设计对照研究方法,抽取湖南省不同地域4家三级甲等医院的197例早产儿做为研究对象,将研究对象按出院后喂养方式分为2组。试验组:采用早产儿出院后配方奶喂养,简称PDF组;对照组:采用足月儿配方奶喂养,简称TF组。收集校正月龄1月、2月、3月时的身高、体重、头围等体格发育指标。采用SPSS 16.0统计软件对资料进行描述性分析和单因素(t、χ2检验)分析。结果试验组早产儿103例,平均出生胎龄(32.31±2.0)周,平均出生体重(1 797.94±426.77)g,平均出生身长(39.17±3.30)cm,平均出生头围(28.40±2.25)cm;对照组早产儿94例,平均胎龄(32.31±2.02)周,平均出生体重(1 807.32±432.15)g,平均出生身长(39.20±3.36)cm,平均出生头围(28.39±2.25)cm。两组间的基本情况差异无统计学意义(P>0.05)。试验组与对照组相比,试验组的身高、体重、头围在校正月龄1月、2月和3月均明显高于对照组,其差异均有统计学意义(P<0.05)。结论使用早产儿出院后配方奶喂养的早产儿体格发育优于足月儿配方奶喂养者。

Objective To evaluate the short term growth of premature infants receiving post-discharge-formula （PDF）. Methods Prospective-controlled trial was employed,and 197 infants in the third-grade class-A hospital from the urban ofHunan were chosen. These infants were classified as post-discharge-formula group （PDF group） and term infant formula group （TF group）. Importantly,monthly weight/length and monthly head circumference were collected from different time. All the data was processed hy the statistic software （SPSS 16.0）.χ2-test and t-test analysis were employed in the process- ing. Results There were no significant differences （P〉0.05）about basic data between PDF group and TF group. In= 103,gestation （32.31±2.0） weeks,birth weight （1 797.9±426. ？7）g,birth length （39.17±3.30）cm,birth head circum- ference （28.40±2.25）cm]VS[n=97,gestation （32.31±2.02） weeks,birth weight（1 807. 32±32.15）g,birth length （39. 20±3.36）cm] ,birth head circumference （28.39±2.25）cm]. But the PDF group had much faster term growth than the TF group at the 1,2 and 3 months after gestational age was corrected. The difference between of them were significant （P〈 0.05）. Conclusion Post-discharge-formula is much better than term infant formula about the growth of infants.