PICU临床药师参与抗感染药物治疗案例分析

Case Study:Clinical Pharmacists Participating in Anti-infection Drug Treatment in PICU

目的探讨临床药师在儿童重症监护病房抗感染药物治疗中的作用。方法通过临床药师参与1例感染性休克患儿抗感染药物治疗过程,与临床医师共同制订治疗方案,监护患者用药全过程,针对患者病情变化提出治疗方案调整。结果临床药师在抗感染治疗进程中,提出监测利奈唑胺血药浓度等建议被临床采纳,充分体现以药动学和药效学理论指导个体化给药。结论临床药师参与医疗团队,协助临床医师调整药物治疗方案,有利于提高药物治疗效果。

OBJECTIVE To investigate the role of clinical pharmacists in anti-infection drug treatment in PICU（Pediatric Intensive Care Unit）. METHODS The clinical pharmacists participated in the anti-infection drug treatment of a child patient, formulated the treatment plan together with the clinical doctors and supervised the whole process of treatment for the patient, then adjusted treatment plan according to the patient＇s changed condition. RESULTS During the anti-infection treatment, clinical pharmacists provided suggestion such as monitoring the plasma concentration of linezolid that were adopted, which reflected applying of pharmacokinetics and pharmacodynamics theories to guide individualized medicine administration. CONCLUSIONS Clinical pharmacists participation in the clinical treatment and corporation with the clinical doctors to adjust the treatment plan can improve the effectiveness of drug treatment.