食物过敏动物模型的研究进展

Research Advances in Animal Models of Food Allergy

食物过敏是食品安全的重要问题之一,日益受到人们的关注。食物过敏动物模型不仅为食物过敏机制的研究提供重要的依据,而且还可有效地对食物过敏原进行准确的评价和检测。本文对小鼠、大鼠、豚鼠等啮齿类动物及幼猪和狗等非啮齿类常见食物过敏动物模型、动物模型致敏途径以及动物过敏模型检测、评价指标等研究进行了综述。

Food allergy is an important food safety issue, and has received more attention recently. Animal models of food allergy are not only necessary to pursue the mechanisms and potential treatments of food allergy, but also become a useful approach to accurate identification and assessment of food allergens. Common animal models of food allergy and their allergic pathways, biological detection methods and allergenicity evaluation are reviewed in this paper.