急性心肌梗塞溶栓治疗的时间窗研究

Study Time Window of Acute Myocardial Infarction Thrombolytic Therapy

目的探究溶栓治疗的时间窗对急性心肌梗死的影响。方法对2009～10～2012-10收治的80位患有急性心肌梗死的患者的临床资料进行回顾分析，根据其发病据治疗时间的长短分为实验组48例（0～6h）和对照组32例（6～12h），根据对时间窗的研究，比较两组患者血管再通率、病死率以及反复心绞痛比率。结果实验组总治疗有效率为91．66％，远高于对照组53．12％，具有统计学意义（P〈0．05）。而对照组较实验组患者出现较多便血、心绞痛等症状。结论急性心肌梗塞发病后6h之内治疗血管的再通性好，病死率低，比发病后6-12h之内治疗效率高。

Objective To discuss thrombolytic therapy time window＇s influences on acute myocardial infarc- tion. Methods Chose 80 cases of those acute myocardial infarction patients who have been admitted at our hospital from October 2009 to October2012 as clinical study objectives, retrospectively analysed their clinical data, divided them into experimental group and control group according to their treatment time, experimental group has 48 cases of patients whose treatment time was 0 to 6 hours, control group has 32 cases of patients whose treatment time was 6 to 12 hours, throughstudy of time window, compared these two groups＇ patients＇ blood vessel recanalization rate, case fatality rate and repeated stenocardia rate. Results Experimental group＇s overall treatment effective rate was 91.66% ,it was far higher than control group＇s 53.12%, it has statistics meaning （ P 〈 O. 05 ）. What＇s more, control group＇s patients suffered from hemafecia and stenocardia more often than experimental group＇s pa- tients. Conclusions It is better for us to treat acute myocardial infarction within six hour of its attack, and this makes contribution to blood vessel recanalization and can reduce case fatality rate, its treatment effective rate is higher than six to twelve hours of attack.