摘要
对内生拟盘多毛孢菌(Pestalotiopsis versicolor)进行大量液体培养,应用多种色谱纯化方法,从其代谢产物中分离得到8个化合物。根据它们的理化性质和波谱数据分别鉴定为:麦角甾醇(1),3β,5α,9α-三羟基-7,22麦角甾二烯-6-酮(2),ergosta-8(9),22-diene-3,5,6,7-tetraol(3β,5α,7α,22E)(3),butyl 2-pyrrolidone-5-carboxylate(4),胸腺嘧啶(5),尿嘧啶(6),邻苯二甲酸正丁酯(7),对羟基苯甲醛(8)。
Endophytic Pestalotiopsis versicolor was fermented in plenty liquid culture, A variety of chromatographic purifi- cation methods were applied, and eight compounds were isolated from its metabolites. Their structure was identified ac- cording to their physicochemical properties and spectral data, they are as follows ： ergosterol （ 1 ）, 3β, 5α, 9α-Trihydroxy- 7,22-ergosterol diene-6-ketone （2）, ergossta-8 （ 9 ）, 22-diene-3,5,6,7-tetraol （ 3β,5α, 7α, 22E ） （3）, butyl 2-pyrroli- done-5-carboxylate （4）, 5-methylpyrimidine-2,4-dione （5）, pyfimidine -2,4-dione （6）, 1,2-benzenedicarboxylic acid, dibutyl ester （ 7 ）,p-hydroxybenzaldehyde （ 8 ）.
出处
《天然产物研究与开发》
CAS
CSCD
北大核心
2014年第2期206-208,217,共4页
Natural Product Research and Development
基金
国家自然科学基金项目(31270402)
