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112例原发性帕金森病病人冲动控制障碍的相关因素分析 被引量:7

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摘要 目的探讨原发性帕金森病冲动控制障碍(ICD)的发生水平及相关因素。方法收集我科帕金森病病人112例,采集病人临床信息,完成相关量表评测,对于可疑行为障碍的病人由专科医生确认。根据有无冲动控制障碍将病人划分为ICD组和非ICD组,分析两组性别、年龄、病程、药物使用等指标的差异,分析可能的危险因素。结果112例病人中8例出现ICD症状,发生率为7.1%。ICD组与非ICD组问在性剐(P〈O.05)、病程(P〈O.001)、是否使用多巴胺受体激动剂(P〈O.02)以及激动剂剂量(P〈0.001)方面差异有统计学意义,进行回归分析后显示病程(OR=1.762,95%C11.177~2.637)与多巴胺激动剂的剂量(0R=1.062,95%CI1.013~1.114)分别与冲动控制障碍具有相关性。结论冲动控制障碍在帕金森病人中并不罕见。较长病程与大剂量多巴胺激动剂是ICD发生的危险因素,使用激动剂很可能与ICD的发生相关。临床上病人与医生对冲动控制障碍的认识均不足,需加强相关症状的识别,减少漏诊。
出处 《中西医结合心脑血管病杂志》 2014年第2期196-198,共3页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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