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D-二聚体对老年转子间骨折内固定术后深静脉血栓形成的价值 被引量:12

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摘要 目的探讨血浆D-二聚体(D-D)水平在老年转子间骨折内固定骨折术后并发深静脉血栓(DVT)诊断中的价值。方法分别在术前、术后第3、7、28天采用免疫比浊法检测413例老年转子间骨折患者血浆D-D水平,同时行双下肢静脉彩超检查作为标准检查。规定血浆D-D水平大于500ng/mL为深静脉血栓阳性,以彩色多普勒检查的阳性结果作为深静脉血栓形成的诊断标准。结果 413名患者中彩超检出48例(11.6%)有急性DVT,D-D检测敏感度93.8%,特异度97.0%,准确度96.6%,阳性预测值80.4%,阴性预测值99.2%,χ2检验P=0.057,D-D水平与彩超具有基本相同的检出率。DVT阳性患者术后第3天平均D-D水平为(743±216)ng/mL,术后第7天为(2 319±563)ng/mL,术后第28天为(2 448±635)ng/mL。与术前比较,差异均有统计学意义(P<0.05)。结论对于检测老年转子间骨折内固定骨折术后DVT形成,D-D检测是一种有效而灵敏的方法。
出处 《重庆医学》 CAS CSCD 北大核心 2014年第6期709-711,共3页 Chongqing medicine
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