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一氧化碳的细胞保护作用及其在临床应用中的研究进展

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摘要 一氧化碳(carbon monoxide ,CO)这种双原子气体,近年来被证实对于体内某些病理情况有着细胞保护作用或诊断价值,其体内主要来源于血红素裂解产物。诸如体内肺损伤所致炎症,CO可减少炎症因子产生从而抗炎;体内细胞凋亡,CO可通过抑制活性氧而阻止细胞死亡;此外,可通过降低炎症因子而对缺血再灌注有保护作用,从而可用于保护器官移植;还可通过测定CO浓度而体现危重病严重度,从而用于重症监护室危重病的监测;基于这些作用,CO对一系列疾病有治疗或诊断作用。现针对其细胞保护作用及其在临床中的应用若干进展作一综述。
出处 《重庆医学》 CAS CSCD 北大核心 2014年第6期751-753,共3页 Chongqing medicine
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