联合检测血清胱抑素C和CRP在新生儿肺炎中的意义

SIGNIFICANCE OF JOINT DETECTION SERUM CYSTATIN C AND CRP IN NEONATAL PNEUMONIA

目的:探讨联合检测血清胱抑素C和C反应蛋白(CRP)对新生儿肺炎诊断意义。方法:采用全自动生化分析仪检测我院2010年1月-2013年1月收治的30例新生儿肺炎患儿血清胱抑素C和CRP的水平,并以同期30例健康新生儿作对照。结果:肺炎组新生儿胱抑素C水平为(1.21±0.30)mg/L、CRP水平为(13.65±3.08)mg/L,肺炎组新生儿胱抑素C的阳性率为66.7%(20/30)、CRP的阳性率为83.3%(25/30),均明显高于健康对照新生儿(P<0.01)。结论:联合检测胱抑素C和CRP可提高新生儿肺炎诊断的敏感度和特异度。

Objective： To explore the diagnostic value of joint detection serum cystatin C and C-reactive protein （CRP） in neonatal pneumonia. Methods：Fully automatic biochemical analyser was used to detect the cystatin C and CRP level of 30 cases neonatal pneumonia from 2010.1 to 2013.1, which were compared with the results of 30 cases healthy newborn at the same term.Results： The serum cystatin C level and CRP level of neonatal pneumonia were respectively （1.21±0.30）mg/L and （13.65＆#177;3.08）mg/L, the positive rate of cystatin C and CRP were 66.7%（20/30） and 83.3%（25/30）, which were all obviously higher than that of healthy newborn （P ＆lt; 0.01）. Conclusions： Joint detection of cystatin C and CRP can raise sensitivity and specificity of neonatal pneumonia diagnosis.