维持性血液透析患者并发心力衰竭相关因素Logistic回归分析

Logistic regression analysis on the related factors for maintenance hemodialysis patients with heart failure

目的探讨维持性血液透析患者并发心力衰竭的相关危险因素,为心力衰竭的预防和治疗提供科学依据。方法回顾性分析125例在我院肾内科进行维持性血液透析患者的临床资料,将患者分为心力衰竭组和非心力衰竭组,用非条件Logistic回归法分析患者心力衰竭发生与患者的年龄、性别、透析龄、血钙、血肌酐、血磷和高血压等13项有关因素的相关性。结果单因素非条件Logistic回归分析结果显示年龄、透析龄、血红蛋白、血清肌酐、血钙、血磷、高血压、高脂血症和心肌病与心力衰竭发生有关,其中年龄、透析龄、血清肌酐、血磷、高血压、高脂血症和心肌病为正相关,血红蛋白、血钙为负相关。多因素回归分析结果显示,透析龄、血红蛋白、血钙、血磷和高脂血症与心力衰竭密切相关。结论维持性血液透析患者并发心力衰竭是多因素作用的结果,透析龄、血红蛋白、血钙、血磷和高脂血症与心力衰竭的发生有密切关系。

Objective To explore the risk factors for heart failure in maintenance hemodialysis patients, and to provide a scientific basis for the prevention and treatment of heart failure. Methods The clinical data of 125 maintenance hemodialysis patients in the Department of Nephrology in our hospital were retrospectively analyzed. The patients were divided into heart failure group and non-heart failure group. Non-conditional logistic regression analysis was applied to analyze the correlation between heart failure and the patient＇s age, sex, duration of dialysis, serum calcium, serum creatinine, phosphorus and hypertension. Results Single factor non-conditional logistic re- gression analysis showed that age, duration of dialysis, hemoglobin, serum creatinine, serum calcium, phosphorus, hypertension, hyperlipidemia, and heart disease, were related to heart failure. Age, duration of dialysis, serum creati- nine, phosphorus, hypertension, hyperlipidemia, and myocardial disease were positively related to heart failure, while hemoglobin and serum calcium were negatively correlated to heart failure. Multivariate regression analysis re- sults showed that the duration of dialysis, hemoglobin, calcium, phosphorus, and hyperlipidemia were closely related to heart failure. Conclusion Hemodialysis patients with heart failure is the result of multiple factors. Duration of di- alysis, hemoglobin, serum calcium, phosphorus, hyperlipidemia and heart failure are closely related.