持续电针联合溴隐亭、美多芭促醒治疗持续性植物状态的临床观察

Clinical observation on continuous electroacupuncture combined with bromocriptine and madopar for arousing consciousness of patients with persistent vegetative states

目的观察持续电针联合溴隐亭、美多芭治疗持续性植物状态(PVS)的疗效。方法 55例持续性植物状态患者随机分成观察组28例和对照组27例。两组均予溴隐亭与美多芭治疗,观察组在上述治疗的基础上联合持续电针治疗,每10 d为一个周期,3个周期及6个周期后分别进行PVS评分,6个周期后评定疗效。结果治疗3个周期后观察组的PVS评分高于对照组,差异有统计学意义(P=0.048);治疗6个周期后,两组差异进一步扩大(P=0.029);6个周期后观察组有效率为85.7%,对照组有效率为55.6%,两组比较差异有统计学意义(P=0.019)。结论持续电针联合溴隐亭、美多芭促醒治疗持续性植物状态有显著疗效。

Objective To observe the clinical efficacy of continous electroacupuncture combined with bro- mocriptine and madopar in yhe treatment of patients with persistent vegetative state （PVS）. Methods Fifty-five pa- tients of PVS were randomly divided into the treatment group （28 cases） and the control group （27 cases）. Both groups were treated with bromocriptine and madopar. The treatment group were additionally treated with continous electroacu- puncture, with every ten days as one cycle. The PVS scores were carried out after 3 and 6 cycles of treatment. The effica- cy was evaluated after 6 cycles of treatment. Results After 3 cycles of treatment, the PVS scores of the treatment group were higher than that of control group, with statistically significant difference between the two groups （P=-0.048）. The difference between the two groups were further expanded after 6 cycles of treatment （P=-0.029）. The effective rate in the treatment group was significantly higher than that in the control group （P=-0.019）. Conclusion Continous elec- troaeupuncture combined with bromocriptine and madopar is significantly effective for persistent vegetative state.