几种含人参皂苷成分中成药制剂的输液管理

Infusion Administration of Ginsenosides in Several Kinds of Traditional Chinese Medicine Preparation

目的观察确定几种含人参皂苷成分的中成药与常用输液配伍后不同时间段内的稳定性,最佳的输注时间和配液、输注方式。方法:将参麦注射液、艾迪注射液、参附注射液、康艾注射液这4种含人参皂苷成分中成药制剂与常见输液配伍,监测0-4h内的性状、pH值、微粒数及吸光度。结果:几种含人参皂苷成分中成药与常见输液配伍后0-4h的性状稳定,液体澄清;吸光度和pH值波动范围小;微粒数在0-2h内波动较大,且部分大于国家标准,2-4h微粒值相对趋于稳定,基本低于国家标准。结论:几种含人参皂苷成分的中成药与常用输液配伍后静置1h左右输注更安全有效,配液时宜缓慢注入药液,减少泡沫的产生。

Objective To determine the stability , the best infusion time and the best way of transfusion and infusion of ginsenosides in several kinds of traditional chinese medicine preparation with common infusion compatibility. Methods： Shenmai injection, Aidi injection, Shenfu injection, and Kang^i injection which all contain ginsenosides mix common infusions within 4 hours and the pH, the number of parti- cles and the absorbance. Results： Several kinds of traditional chinese medicine preparation which contain ginsenoside are stable after mixig common infusions in 0 - 4hours, hauve clear liquid and small fluctuation range of absorbance and PH value; the numberof particles has large fluctuation wihtin 0 - 2 hours and greater than national standards, praticles value in 2 - 4 hours tend to be relatively stable, and is basically be- low the national standard.