中西医结合三联疗法治疗晚期癌症厌食症临床观察

Clinical Observation of Triple Therapies Combining TCM and Western Medicine on Anorexia during Advanced Cancer

目的观察治疗晚期癌症厌食症的临床方法。方法采用中药健脾消食方、耳穴贴敷治疗及口服醋酸甲地孕酮分散片组成的三联疗法,治疗240例晚期癌症厌食症,并与口服孕激素醋酸甲地孕酮分散片及对症支持疗法对照。结果治疗结束后,治疗组食欲改善总有效率94.2%,优于对照组68.7%(P<0.05),治疗组卡氏评分、体重、血清白蛋白、前白蛋白水平改善程度均优于对照组。结论以中药健脾消食方、耳穴治疗及口服醋酸甲地孕酮分散片中西医结合三联疗法治疗晚期癌症厌食症有较好的疗效。

Objective To explore the clinical approach to anorexia during advanced cancer. Methods Two hundred and forty eases of anorexia with advanced cancer were observed by using triple therapies combining Chinese herbs of invigorating spleen to promote digestion, auricular acupoint application with orally taking megestrol acetate, Symptomatic support therapy and orally taking megestrol acetate were set up as control group. Results Total effective rate of appetite improvement in treatment group was significantly better that that of control group （94.2% vs 68.7% ,P 〈 0.05 ）. Improvements in Karnofsky performance score, weight, serum albumin and prealbumin level of treatment group were also better than those of control group respectively. Conclusion Triple therapies including Chinese herbs of invigorating spleen to promote digestion, auricular acupoint application and orally taking megestrol acetate are better method for the treatment of anorexia during ad- vaneed cancer.