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直肠胃肠道间质瘤的外科治疗 被引量:4

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摘要 分析直肠胃肠道间质瘤患者的临床特点、病理特征、外科治疗效果,探讨影响治疗效果的相关因素,直肠胃肠道间质瘤的临床特点及外科治疗效果。直肠胃肠道间质瘤多属于高危风险,术后生存率与年龄、性别、肿瘤部位、大小、核分裂相、增值指数、手术根治程度、术后药物治疗的单因素分析结果显示,根治性手术与姑息性手术相比较,术后生存差异有显著差异(P<0.01)。根治性手术是延长直肠胃肠道间质瘤患者生存时间的主要因素,靶向治疗可提高直肠胃肠道间质瘤的保肛率。
出处 《中国现代普通外科进展》 CAS 2014年第1期42-44,共3页 Chinese Journal of Current Advances in General Surgery
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参考文献15

  • 1Wasag B, Debiec-Ryehter M, Pauwels P, et al . Differential expres- sion of KIT/PDGFRA mutant isoforms in epithelioid and mixed variants of gastrointestinal stromal tumors depends predominantly on the tumor site[J]. Mod Pathol, 2004,17:889-94.
  • 2Miettinen M, Sobin LH, Sarlomo-Rikala M. lmmunohis-tochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117(KIT)[J]. Mod Pathol, 2000,13:1134-42.
  • 3贾文焯,孙建华,黄美雄.胃肠道间质瘤86例诊治分析[J].中国现代普通外科进展,2009,12(3):271-272. 被引量:2
  • 4Joensuu H. Risk stratification of patients diagnosed with gastroin- testinal stromal tumor[J]. Human pathology, 2008,39(10):1411-1419.
  • 5B Nilsson, P Biimming, JM Meis et al .Gastrointestinal stromal tu- mors: The incidence, prevalence, clinical course, and prognostica- tion in the preimatinib mesylate era[J]. Cancer, 2005,103 (15):821- 829.
  • 6Duffaud F, Cassier P A, Adenis A, et at. Gastrointestinal stromal tumor (GIST) of the rectum and pararectal space: A French Sarco- ma Group (FSG) retrospective review[C]//& Clin Oncol (Meeting Abstracts), 2010,28( 15 suppl):10055.
  • 7Tielen R, Verhoef C, van Coevorden F, et al, Surgery after treatment with imatinib and/or sunitinib in patients with metastasized gas- trointestinal stromal tumors: is it worthwhile[J]. World Journal of Sur- gical Oncology, 2012,10(1):111.
  • 8Joensuu H, DeMatteo RP. The management of gastrointestinal stro- mat tumors: a model for targeted and muhidisciplinary therapy of malignancy[J]. Annual review of medicine, 2012,63:247-258.
  • 9Joensuu H, Eriksson M, Hatrmann J, et at. Twelve versus 36 months of adjuvant imatinib (1M) as treatment of operable GIST with a high risk of recurrence: final results of a randomized trial (SS- GXVIII/AIO)[J]. J Clin Oneol, 2011,29(18):381-383.
  • 10Gramza AW, Corless CL, Heinrich MC. Resistance to tyrosine ki- nase inhibitors in gastrointestinal stromal tumors[d]. Clinical Can- cer Research, 2009,15(24):7510-7518.

二级参考文献13

  • 1Mazur MT, Clark HB. Gastric stromal tumors. Reappraisal of histogenesis[J]. Am J Surg Pathol, 1983,7(6):507.
  • 2Miettinen M, Lasota J. Gastrointestinal stromal tumors definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis [J]. Virchows Arch, 2001,438(1):1.
  • 3Heinrich MC, Corless CL. Gastric GI Stromal tumors(GISTs): the role of surgery in the era of targeted therapy[J]. J Surg Oncol, 2005,90(3):195-207.
  • 4Lewin KJ, Riddell RH, Weinstein WM. et al. Gastrointestinal pathology and its clinical implications[M]. New York:Igaku-shoin,1992:284-341.
  • 5Casper ES, Gastrointestinal stromal tumors[J]. Curr Treat Options Oncol, 2000,1:267.
  • 6Tamiolakis DJ, Venizelos ID, Cheva AD, et al. Fine needle aspiration cytology diagnosis of gastrointestinal stromal tumors utilizing scanning electron microscopy[J]. Medicina (Kaunas), 2005,41(2):117-122.
  • 7Neuhaus SJ, Clark MA, Hayes AJ, et al. Surgery for gastro-intestinal stromal tumour in the post-imatinib era[J]. ANZ JSurg, 2005,75(3):165-172.
  • 8Rossi CR, MocellinS, MencarelliR, et al. Gastrointestinal stromal tumors:from a surgical to a molecul arapproach[J]. Int J Cancer, 2003,107(2):171-176.
  • 9Mochizuki Y, Kodera Y, Fujiwara M, et al. Laparoscopic wedge resection for gastrointestinal stromal tumors of the stomach :initial experience[J]. Surg Today, 2006,36(4):341-347.
  • 10Novitsky YW, Kercher KW, Sing RF, et al. Long-term outcomes of laparoscopic resection of gastric gastrointestinal stromal tumors[J]. Ann Surg, 2006,243:738-745.

共引文献1

同被引文献36

  • 1王海.浅谈胃肠道间质瘤的病理特点及诊治方法[J].当代医药论丛,2014,12(6):238-240. 被引量:1
  • 2Duffaud F, Blay J Y. Gastrointestinal stromal tumors: bi- ology and treatment [ J ]. Oncology, 2003,65 ( 3 ) : 187- 197.
  • 3Yokoi K, Yamashita K, Tanaka N, et al. Gastrointestinal stromal tumor of the stomach diagnosed preoperatively [J]. J Nippon Med Sch, 2001,68(5) :435-441.
  • 4Casali P G, Blay J Y. Gastrointestinal stromal tumours: ESMO Clinical Practice Guidelines for diagnosis, treat- ment and follow-up [ J ]. Ann Oncol, 2010,21 ( Suppl 5iN) :98-102.
  • 5Fletcher C D, Berman J J, Corless C, et al. Diagnosis of gastrointestinal stromal tumors: A consensus approach [ J ]. Hum Pathol, 2002,33 ( 5 ) :459-465.
  • 6Koehhar R, Manoharan P, Leahy M, et al. Imaging in gastrointestinal stromal tumours: current status and future directions [ J ]. Clin Radiol, 2010,65 ( 8 ) :584-592.
  • 7Hornick L J, Fletcher C D. The role of KIT in the man- agement of patients with gastrointestinal stromal tumors [J]. HumPathol, 2007,38(5):679-687.
  • 8史伟,王强,李州利,石炳毅,蔡明.直肠部位胃肠间质瘤1例报告并文献复习[J].中国误诊学杂志,2008,8(3):735-736. 被引量:2
  • 9刘骞.直肠间质瘤的外科治疗[J].实用肿瘤杂志,2009,24(2):102-103. 被引量:10
  • 10王保华,张冠南,肖毅,邱辉忠.直肠间质瘤的临床病理特点及诊治[J].基础医学与临床,2009,29(8):888-891. 被引量:4

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