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胃癌根治术前行FOLFOX新辅助化疗的作用评估 被引量:2

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摘要 选取2011年8月—2012年8月应用FOLFOX(奥沙利铂+氟尿嘧啶+亚叶酸钙)的新辅助化疗方案治疗不能一次性切除的高度进展期胃癌15例,并与同期应用伊立替康联合替加氟治疗的15例高度进展期胃癌患者对比。FOLFOX新辅助化疗方案相对于伊立替康联合替加氟治疗的方案在近期疗效、毒副作用等方面具有一定的优势,2组总有效率分别为73.3%、40.0%,差异有统计学意义(P<0.05);在消化系统毒性和神经毒性方面,2组差异有统计学意义(P<0.05)。FOLFOX新辅助化疗方案临床治疗效果较好,患者的毒副反应小,将成为进展期胃癌综合治疗中不可或缺的一个环节。
出处 《中国现代普通外科进展》 CAS 2014年第1期63-65,共3页 Chinese Journal of Current Advances in General Surgery
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参考文献7

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