血清药理学在中药药效学中的研究进展

Research Advance of Serum Pharmacology in Traditional Chinese Medicine Pharmacodynamics

血清药理学是使用药物给予动物灌胃后一定时间所得血清进行体外研究的新方法。通过对血清药理学方法在中药药效学研究中建立的试验方案进行对比后,发现其应用所得试验结果的好坏与该方法的动物选择、给药剂量与时间、取血时间与血清的处理等均有紧密的关系,因此对近年来血清药理学方法在中药药效学的方法学研究进行了文献综述,为血清药理学方法在中药以及中药复方研究中的使用提供理论依据。

Serum pharmacology refers to a method that animal serum is taken in a certain time to study the role of traditional Chinese medicine in vitro after animals orally given medicine or herbal compound. The application of the method has a close relationship with their animal selec-tion, dose and time, blood serum processing time and so on, as obtained through comparison research on the serum pharmacology studies in med-icine pharmacodynarnics experimental programs. Literatures about serum pharmacology in traditional Chinese medicine pharmacodynamics were reviewed, so as to provide scientific theoretical basis for utilization of serum pharmacology in traditional Chinese medicine.