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心房颤动发病机制研究进展 被引量：6

Progression of pathogenesis of atrial fibrillation
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摘要 心房颤动是最常见的阵发性或持续性心律失常,且随年龄增大其发病率逐渐增加。房颤可诱发栓塞风险,在高原地区更为严重,干扰心室泵血功能,加重心肌损伤。本文就心房解剖、心房肌细胞电生理、心律失常发生机制及心房颤动发生机制等研究进展做一述评。 The atrial fibrillation is the most frequent fibrillation. It＇s incidence increases with the age. The atrial fibrillation can induce embolism, interfere blood-pumping function of ventricles and aggravate myocardial damage. The present article describes the anatomy of atrium, the electrophysiology of atrial muscle cell and the mechanisms of arrhyth- mogenesis and atrial fibrillation.
作者 柳茵 丁绍祥
机构地区 青海大学附属医院心内科 青海省康乐医院
出处 《西部医学》 2014年第3期269-271,共3页 Medical Journal of West China
基金 国家自然科学基金(8160012)
关键词 心律失常 房颤 离子流 电重构 Arrhythmogenesis Atrial fibrillation Lonic flow Electronic reconfiguration
分类号 R541.75 [医药卫生—心血管疾病]
  • 相关文献

参考文献17

  • 1Olesen MS,Bentzen BH, Nielsen JB, et al. Mutations in the po- tassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation[J]. BMC Med Gcnet, 2012,13 : 24.
  • 2Bao L,Kefaloyianni E, Lader J, et al. Unique properties of the ATP-sensitive K+ channel in the mouse ventricular cardiac con- duction system[J]. Circ Arrhythm Electrophysiol, 2011,4 (6) : 926-935.
  • 3Schmidt C,Wiedmann F, Schweizer PA, et al. Cardiac two-pore- domain potassium channels(K2P) : Physiology, pharmacology, and therapeutic potential[J]. Dtseh Med Wochenschr, 2012,137 (33) : 1654-1658.
  • 4Wirka RC,Gore S,Van Wagoner DR,et al. A common eonnexin- 40 gene promoter variant affects eonnexin-40 expression in hu- man atria and is associated with atrial fibrillation[J]. Cire Ar- rhythm Electrophysiol,2011,4(1) :87-93.
  • 5Auerbach DS, Grzda KR, Furspan PB, et al. Structural heteroge- neity promotes triggered activity, reflection and arrhythmogene- sis in eardiomyocyte monolayers[J]. J Physiol,2011,589(Pt 9): 2363-2381.
  • 6丁绍祥.J波和2相折返形成离子流机制研究进展[J].中国老年学杂志,2012,32(12):2676-2678. 被引量：12
  • 7De Lange E, Xie Y, Qu Z. Synchronization of early afterdepolar- izations and arrhythmogenesis in heterogeneous cardiac tissue models[J]. Biophys J,2012,103(2) :365-373.
  • 8Pellman J, Lyon RC, Sheikh F. Extracellular matrix remodellngin atrial fibrosis: mechanisms and implications in atrial fibrillation [J]. J Mol Cell Cardiol,2010,48(3) :461-467.
  • 9丁绍祥.早复极发生机制的研究进展[J].天津医药,2012,40(10):1081-1084. 被引量：10
  • 10丁绍祥.关于结间束存在的合理性探讨[J].中国医疗前沿,2009,4(18):9-9. 被引量：2

二级参考文献35

  • 1Jastrzebski M, Kukla P. Ischemic J wave: novel risk marker for ventrlcular fibrillation[J]. Heart Rhythm,2009 ;6:829-35.
  • 2杨新春,李延辉.原发性心电疾病心电图.见:陈新,黄宛.临床心电图学[M].北京:人民卫生出版社,2009:141-65.
  • 3崔长琮,梁一木.心室复极波的离子流机制与心电图[M].见:郭继鸿,崔长琮.抗心律失常中西药与离子通道.北京:人民卫生出版社.2008:239-45.
  • 4Antzelevitch I-I. Heterogeneity and cardiac arrhythmias:An overview[J]. Heart Rhythm ,2007 ;4:964-75.
  • 5Sabir IN, Li LM, Grace AA. Restitution analysis of ahemans and its rela- tionship to arrhythmic genieity in hypokalemie langertdorff-perfused mu- rine hearts[J].Pflugers Arch,2008 ;455:653-66.
  • 6傅向华.低血钾相关性恶性室性心律失常[M].胡大一,马长生.心脏病学实践2009.新进展与临床案例.北京:人民卫生出版社,2009:212-22.
  • 7Moss A J, Schwartz PJ. Anniversary of the international long QT syn- drome registry:an ongoing quest to uncover the secrets of long-QT syn- drome [ J ]. Circulation,2005 ; 111 : 1199-201.
  • 8Antzelevitch C. Brugada syndrome[J].PACE ,2006 ;29 : 1130-59.
  • 9Morita H, Zipes DP, Lopshire J, et al. Temperature modulation of ven- tricular arrhythmogenicity in a canine tissue model of Bmgada syndrome[J]. Heart Rhythm ,2007 ;4 : 188-97.
  • 10Antzelevitch C, Polleviek GD, Cordeiro JM, et al, Loss-of-function muta- tions in the cardiac Calcium channel underlie a new clinical entity char-acterized by ST-segment elevation, short QT intervals and sudden cardi- ac death[ J]. Circulation ,2007 ; 115:442-9.

共引文献13

同被引文献70

  • 1周自强,胡大一,陈捷,张仁汉,李奎宝,赵秀丽.中国心房颤动现状的流行病学研究[J].中华内科杂志,2004,43(7):491-494. 被引量：1398
  • 2陈贵廷 薛赛琴.最新国内外疾病诊疗标准[M].北京：学苑出版社,1991..
  • 3Kearney K, Stephenson R, Phan K, et al. A systematic review of surgical ablation versus catheter ablation for atrial fibrillation[J]. Annals of Cardiothoracic Surgery, 2014, 3 (1): 15-29.
  • 4Ferguson Jr TB, Schuessler RB, Hand DE, et al. Lessons learned from computerized mapping of the atrium. Surgery for atrial fibrillation and atrial flutter [J ]. Journal of Electrocardiology, 1992, 26: 210-219.
  • 5Handa N, Schaff HV, Morris JJ, et al. Outcome of valve repair and the Cox maze procedure for mitral regurgitation and associated atrial fibrillation[J]. The Journal of Thoracic and Cardiovascular Surgery, 1999, 118(4): 628-635.
  • 6Robertsun JO, Lawrance CP, Maniar HS, et al. Surgical Techniques Used for the Treatment of Atrial Fibrillation[J]. Circulation Journal Official Journal of the Japanese Circulation Society, 2013,77(8): 1941-1951.
  • 7La Meir M, Gelsomino S, Luco F, et al. Minimal invasive surgery for atrial fibrillation: an updated review [J]. Europace, 2013, 15(2): 170-182.
  • 8Kim JB, Yun TJ, Chung CH, et al. Long-term outcome of modified maze procedure combined with mitral valve surgery: analysis of outcomes according to type of mitral valve surgery [J]. The Journal of Thoracic and Cardiovascular Surgery, 2010, 139(1): 111-117.
  • 9Shen J, Bailey MS, Damiano RJ Jr. The surgical treatment of atrial fibrillation[J]. Heart Rhythm, 2009, 6(8 Suppl) $45- 50.
  • 10刘培良,黄峥.143例老年阵发性心房颤动患者的临床观察与分析[J].中国循环杂志,2014,29(增刊):167.

引证文献6

二级引证文献22

西部医学
2014年 第3期

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