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IL-8与结直肠癌 被引量：4

IL-8 and colorectal cancer
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摘要 IL-8是一种多源性趋化因子,由单核细胞、内皮细胞等多种细胞合成与释放。IL-8在结直肠癌患者体内表达增高,IL-8血清水平的提高有助于结直肠癌患者病情监测。IL-8通过多种途径增强结直肠癌的肿瘤干细胞样特性,促进结直肠癌的血管形成、增生与转移等生物学活性。本文对IL-8与结直肠癌之间的关系进行综述。 IL-8 expression increases in patients of colorectal cancer , and the serum level of IL-8 contributes to monito-ring colorectal cancer .There also have been some studies investigating the relationship between IL -8 gene and colorectal cancer.IL-8 increases cancer stem cell characteristics through a variety of ways , such as promoting angiogenesis , prolif-eration, metastasis and other biological activities of colorectal cancer .These studies provide novel approaches for prevention and treatment of colorectal cancer .
作者 程慧 李芳
机构地区 大连医科大学 大连医科大学基础医学院免疫学教研室
出处 《大连医科大学学报》 CAS 2014年第1期95-97,共3页 Journal of Dalian Medical University
关键词 IL-8血清水平与基因 结直肠癌 生物学活性 IL-8 serum level and IL-8 gene colorectal cancer biological activities
分类号 R735.3 [医药卫生—肿瘤]
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共引文献92

同被引文献54

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大连医科大学学报
2014年 第1期

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