155例非酒精性脂肪肝患者的中医证候学研究

The traditional Chinese medical syndrome study on 155 patients with non-alcoholic fatty liver disease

目的 研究非酒精性脂肪肝（non-alcoholic fatty liver disease,NAFLD）的证候特征,为进一步探讨其发病机制打下基础.方法 采取横断面的方法,制定临床证候调查表,全面收集NAFLD患者一般临床资料和中医四诊所得症状资料,进行统计分析.结果 NAFLD患者各个年龄组均有发生,以40~50岁年龄组所占比例最大,占总例数的34.2%,男女发病比例为3.07∶1.中医证侯依次为肝郁脾虚（39.4%）、痰湿内阻（24.5%）、痰瘀互结（18.7%）、肝肾不足（9.8%）和湿热内蕴（7.6%）.结论 脾虚肝郁是NAFLD最常见的证候,而痰湿是其发病的重要因素.

Objective To study the characteristics of the traditional Chinese medicial （TCM） syndrome of non-alcoholic fatty liver disease （NAFLD）, laying the foundation for further study its pathogenesis. Methods The clinical symptom questionnaire was developed and the cross-sectional research method was adopted. The comprehensive clinical data of patients with NAFLD was collected and TCM symptom data were collected for statistical analysis. Results In all age groups of patients with NAFLD have occurred to the 40 -50 age group the largest proportion of the total number of cases 34. 2% ; the ratio of male to female NAFLD patients was 3.07： 1. The incidence of TCM syndrome was liver-stagnation and spleen-deficiency （39.4%）, phlegm-damp accumulating （24. 5% ）, phlegm and blood knot （ 18.7% ）, deficiency of liver and kidney （9. 8% ）, and dampness-heat accumulating （7.6%）. Conclusion Liver-stagnation and spleen-deficiency is the most common TCM syndrome in NAFLD patients, and phlegm is an important factor in its incidence.