胆道铸型综合征的发病机制与诊治

Pathogenesis, diagnosis and management of biliary cast syndrome

胆道铸型综合征(BCS)是指肝移植术后充填于肝内外胆道的坏死物质形成胆道树样的铸型,并由此引起的一系列临床表现,是肝移植术后少见但非常严重的并发症。了解BCS的病因、发病机制以及临床表现,有助于预防BCS的发生,提高肝移植术后BCS患者的生存率,笔者就此及BCS的诊治方面作一综述。

Biliary cast syndrome （BCS） is defined as the necrotic debris filling the intra- or extra-hepatic biliary tracts and forming casts that take the shape of the biliary tree after liver transplantation, thus leading to a series of clinical manifestations. It is an unusual but very serious complication of liver transplantation. A better knowledge of the etiologypathogenesis and clinical features of BCS may help prevent the occurrence of BCS and improve the survival of post-liver transplantation BCS patients, thus, the authors address the related issues along with the diagnosis and treatment of this condition.