广东省东莞市糖尿病视网膜病变流行病学调查

Prevalence of diabetic retinopathy in Dongguan city,Guangdong Province,China

目的调查东莞市横沥镇40岁及以上常住户籍居民糖尿病视网膜病变(diabetic retinopathy,DR)的患病率。方法采取以人群为基础的横断面流行病学调查。对广东省东莞市横沥镇16个自然村和1个社区户籍居民≥40岁的常住人口进行普查。调查包括:居民基本信息、糖尿病(diabetes mellitus,DM)和DR问卷、身体测量、实验室检查和眼科专科检查等。根据2010年美国ADA DM诊断标准确诊DM,并根据2002年悉尼DR国际分型标准进一步进行DR筛查和分级。着重分析DR的患病情况。结果应参加普查的横沥镇常住居民11 181人,实际调查8952人,应答率为80.06%,共筛查出DM患者1508人,DM患病率为16.85%。1508例DM患者中新诊断DM患者1072人(71.09%),有DM病史者436人(28.91%)。1508例DM患者1310例眼底照片可判读,共筛查出DR 239例,DR患病率为18.24%,标准化后为18.20%,其中非增生型DR患病率为17.33%,增生型DR患病率为0.92%。结论广东省东莞市横沥镇40岁及以上居民DR患病率为18.20%,其中非增生型DR占主要部分,即多数患者处于疾病的早期和中期阶段,需要得到及时的干预和治疗。

Objective To describe the diabetic retinopathy （DR） prevalence of Han Chinese aged 40 years or older in Hengli town-, Donggtmn city in Southern China. Methods A population-based cross-sectional study. The Han Chinese aged 40 years or older from 16 villages and a community participated in the census of diabetes. Partici- pants underwent standardized interview, physical and ocular examinations, including general messages （ name, gender and age）, social and economic situation （ occupation, education level, income）, questionnaire of diabetes and diabetic retinopathy, anthropom- etry, laboratory examination. Ocular examination included visual acuity, intraocular pressure, anterior and posterior segment examinatiolts, ftmdus and optic disc photogra- phy. The diagnosis of diabetes mellitus（DM） and DR were made according to ADA diag- nostic criteria（American,2010） for diabetes and international clinical classification sys- tem of DR and DME（Sydney,2002）. Results Of ll 181 eligible persons,8592 were examined,and response rate was 80.06%. 1508 participants were diagnosed with diabe- tes mellitus in field investigation, and 69 diabetic patients were screened out from the telephone survey. The prevalence of diabetes mellitus was 16.85%. Among 1508 diabetic patients,1072 cases （71.09%） were newly diagnosed and 436 cases （28.91%） with known DM. In 1508 cases with DM, the fundus photography in 1310 cases could be judged,239 cases （ 18. 24% ） with DR were screened, the standard prevalence was 18. 20% ,in which the prevalence of non-proliferative DR was 17.33% and the prolifera- tive DR was 0. 92%. Conclusion The DR prevalence of Han Chinese aged 40 years or older in Hengli town, Dongguan city is 18. 20% , in which non-proliferative DR is more common, most of the people are in the early and mid stage of DR, which need the pre- vention and treatment in time.