银杏叶提取物治疗短暂性脑缺血发作的疗效观察

Curative effect of Ginkgo biloba extract in the treatment of transient ischemic attack

目的探讨银杏叶提取物治疗短暂性脑缺血发作患者的效果及安全性。方法将66例患者随机分为观察组34例和对照组32例,观察组患者采用银杏叶提取物治疗,对照组患者采用低分子右旋糖酐治疗,观察两组患者的治疗效果、不良反应以及血液流变学变化。结果治疗10d后,对照组总有效率为65.63%,观察组总有效率为94.12%,两组比较差异有统计学意义(P<0.05)。对照组血液流变学各指标较治疗前有变化,但差异无统计学意义(P>0.05);观察组患者各指标较治疗前有明显变化(P<0.05);两组比较,差异有统计学意义(P<0.05)。结论银杏叶提取物能明显改善短暂性脑缺血患者的临床症状,降低血液黏稠度,疗效确切且不良反应较少,值得临床推广应用。

Objective To study the efficacy and safety of Ginkgo Biloba extract （skinner） for the treatment of transient ischemic attack. Methods 66 patients were randomly divided into observation group and control group, 32 cases in observation group were treated with skinner treatment, while 34 cases in control group were treated with low molecular dextran treatment, observed the therapeutic effect, adverse reactions and the change of blood rheology of the two groups. Results 10 days after treatment, the total effective rate of control group was 65.63%, while the observation group was 94.12%, there were significant differences between the two groups（P ＆lt; 0.05）. The blood rheological index of control group changed than before treatment, but without significant difference（P＆gt;0.05）, while the treatment group changed obviously, with significant differences （P＆lt;0.05）, and there were significant differences between the two groups（P ＆lt; 0.05）. Conclusion Ginkgo Biloba extract can significantly improve the clinical symptoms of transient ischemic attack, reduce blood viscosity, and has less adverse reactions, so it＆#39;s worthy of clinical popularization and application.