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静脉滴注阿昔洛韦与口服盐酸伐昔洛韦治疗带状疱疹多中心随机对照研究 被引量:26

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摘要 阿昔洛韦(acyclovir,ACV)是治疗带状疱疹经典的抗病毒药物,因其口服生物利用度仅10%--20%,常需静脉给药以提高血药浓度。盐酸伐昔洛韦(valaciclovirhydrochloride,VACV)是ACV的前体药物,水溶性好,口服生物利用度可达ACV的3。5倍,成为治疗带状疱疹的常用方法。我们组织开展了多中心、随机开放、平行对照临床研究,比较静脉滴注ACV与口服VACV治疗带状疱疹的疗效和安全性。
出处 《中华皮肤科杂志》 CAS CSCD 北大核心 2014年第3期217-219,共3页 Chinese Journal of Dermatology
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