以水痘样疹为主要表现的Stevens-Johnson综合征

A case of Stevens-Johnson syndrome presented as chickenpox-like lesions

报告1例以水痘样疹为主要皮损表现的Stevens-Johnson综合征。患儿女,13岁。因全身红斑、水疱14 d入院,水疱形态类似水痘,伴高热。丙氨酸转氨酶升高,水痘-带状疱疹病毒抗体IgM阴性,皮损组织病理符合多形红斑型药疹改变。诊断为Stevens-Johnson综合征,予糖皮质激素联合抗感染治疗后好转。强调了对于难以立刻确诊的危重病例,快速诊断、权衡利弊及果断决定治疗方案的重要性。

A 13-year-old girl suffered from high fever, generalized erythema and blisters for 14 days. The blisters were similar to the lesions of ehickenpox. The aminotransferase was elevated and chickenpox antibody IgM was negative. The histopathology revealed drug eruption of erythema muhiforme. A diagnosis of Stevens-Johnson syndrome was made and the patient got better after given systemic eorticosteroid and antibiotics. The present case suggests that it is critical to quickly diagnose arid make therapeutic decision for cases with difficulty to diagnose immediately.