动态容积320排冠状动脉CT血管成像诊断冠状动脉疾病的意义

Diagnosis of coronary artery disease with dynamic volume 320-slice coronary CT angiography

目的:研究320排动态容积冠状动脉CT成像(CCTA)诊断冠状动脉疾病(CAD)的可行性。方法:5 961例临床诊断CAD的患者进行CCTA检查,其中186例接受常规X线冠状动脉造影术(CAG),对照分析其检查结果。1 490例接受CCTA检查的健康查体者作为对照。结果:成像质量均在I^III级,无呼吸伪影图像。在186例CAD患者中,CCTA诊断冠状动脉狭窄(狭窄度≥50%)的敏感性为96.72%,特异性98.95%,阳性预测值95.16%,阴性预测值99.30%,准确度98.56%。结论:320排动态容积CT冠状动脉成像图像清晰,对诊断CAD具有重要的临床价值。

Objective： To investigate the feasibility of diagnosis of coronary artery disease （CAD） with dynamic volume 320--slice coronary CT angiography （CCTA）. Methods： The CCTA was performed in 5 961 patients with CAD diaunosed clinically,186 patients in them received the conventional X--ray coronary angiography （CAG）, and the examination results were compared between CCTA and GAG. The control group for the image quality consisted of 1 490 healthy individuals receiving CCTA. Results： The image quality of CCTA all ranged from I to III grade levels, without respiratory artifacts. In 186 CAD patients undergoing CAG, the sensitivity of CCTA for diagnosis of coronary stenosis （degree ≥50%） was 96.72%, specificity was 98. 95% 99.30%, and accuracy was identification of CAD and may be positive predictive value was 95. 16%, negative predictive value was98.56 %, Conclusion： The CCTA could provide high--quality images for the an important diagnosis tool for CAD patients.