弥漫性轴索损伤患者并发下肢深静脉血栓的相关因素分析

Correlative factors analysis of diffuse axonal injury patients with deep veins thrombosis in lower limbs

目的 探讨弥漫性轴索损伤（DAI）患者并发下肢深静脉血栓（LDVT）的危险因素和预防策略.方法 对130例DAI患者进行双下肢血管超声检查,根据是否发生LDVT分为LDVT组22例和非LDVT组108例,对患者长期卧床、血浆纤维蛋白原、股静脉穿刺、静脉曲张、高血压、性别、吸烟、饮酒、糖尿病、肥胖、G CS评分等相关因素进行分析.结果 LDVT组与非LDVT组比较,患者长期卧床、高血压、吸烟、糖尿病、高血浆纤维蛋白原、GCS评分、年龄差异均有统计学意义（x2值分别为7.08、5.99、5.17、4.70、3.55、12.72,t =27.80;P均＜0.05）；而性别、饮酒、肥胖、静脉曲张因素比较差异均无统计学意义（P均＞0.05）.结论 DAI合并LDVT患者多见于年龄偏大、长期卧床、高血压、吸烟、糖尿病、GCS评分低、血浆纤维蛋白原较高者.

Objective To investigate the risk factors and preventive strategies of patients with diffuse axonal injury（DAI） with deep veins thrombosis in lower limbs （LDVT）.Methods One hundred and thirty cases of diffuse axonal injury patients with lower limb vascular were divided into LDVT group（22 cases） and non LDVT group（108 cases） based on ultrasound.The information including long-term bed,plasma fibrinogen level,varicose veins,hypertention,sex,age,smoking,alcohol drinking,diabetes,obesity,Glasgow Coma Scale （GCS） were collected.Results There were significant different between LDVT and non-LDVT group in terms of longterm bed time,hypertension,smoking,diabetes,high plasma fibrinogen,age,low GCS score correlated with LDVT （x2 =7.08,5.99,5.17,4.70,3.55,12.72,t =27.80,P ＜ 0.05）.Gender,drinking,obesity,varicose vein factors had no correlation with LDVT（P ＞ 0.05）.Conclusion Diffuse axonal injury in patients with LDVT is more common in patients with older age,hypertension,low GCS score,the higher the plasma fibrinogen.