注意缺陷多动障碍儿童的认知功能研究

Study on the cognition function profiles in children with attention deficit hyperactivity disorder

目的探讨注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)儿童的认知功能损害特征。方法应用威斯康星卡片分类测验(Wisconsin Card Sorting Test,WCST)分别对注意缺陷多动障碍儿童组(ADHD组)和正常儿童对照组(HC组)的认知功能进行神经心理学测试。结果威斯康星卡片分类测验中5项指标:完成分类数(Categories control,CC)、错误应答数(Responses Errors,Re)、概念化水平(Rfp)、持续性错误数(Preservative Errors,Rpe)、持续性应答数(Preservative Responses,Rp),在注意缺陷多动障碍儿童组与正常对照组的比较显示,其差异具有统计学意义(P<0.05或<0.01);经两两比较不同亚型注意缺陷多动障碍组的WCST 5项指标,其差异亦具有统计学意义(P<0.05或<0.01)。结论注意缺陷多动障碍儿童存在一定程度的认知功能损害;不同亚型注意缺陷多动障碍儿童的认知功能损害程度有所不同。

Objective To investigate the characteristics of the cognition function damage of children with attention def- icit hyperactivity disorder （ADHD）. Methods Wisconsin Card Sorting Test （WCST） was carried out to detect the reac- tion of neural and psychology on the cognition function of children with ADHD and health control respectively. Results There were a significant differences in each index of WCST （CC, Re, Rfp, Rpe, Rp）between the ADHD group and control group（P〈0.05 or 〈0.01）. Comparison in each index of WCST showed that there were a statistically significances between subtypes of children with ADHD（P〈0.05 or 〈0.01）. Conclusion The cognition function damage exists in children with ADHD,and the extent of damage differs between the various subtypes.