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应用定标活检技术优选慢性萎缩性胃炎的治疗疗程 被引量:9

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摘要 慢性萎缩性胃炎(chronic atrophic gastritis,CAG)是消化系统常见疾病,因其每年1%~3%^[1]的高癌变率而被认为是胃癌的癌前期病变,因此预防CAG癌变具有十分重要的临床意义。目前临床上由于缺乏可靠的随访手段,还没有十分可信的逆转CAG的治疗方案和合适的治疗疗程。为此,本研究对326例CAG患者分组后分别应用替普瑞酮联合叶酸治疗或非特异性治疗,采用定标活检(marking targeting biopsy,MTB)技术观察不同治疗时间点的临床效果,为CAG的疗程选择提供依据。
出处 《中华内科杂志》 CAS CSCD 北大核心 2014年第3期210-212,共3页 Chinese Journal of Internal Medicine
基金 卫生部科学研究基金(省部共建)(WKJ2010-2-012)
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  • 1朱舜时,李蓉蓉,施尧,燕善军,袁济民,萧树东,江绍基.胃癌患者胃粘膜细胞内维生素的变化[J].中华消化杂志,1994,14(1):28-30. 被引量:16
  • 2Kang GH, Lee S, Kim JS, Jung HY. Profile of aberrant CpG island methylation along the multistep pathway of gastric carcinogengesis. Lab Invest 2003; 83:635-641.
  • 3Tamura G. Promoter methylation status of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia. Histol Histopathol 2004;19:221-228.
  • 4Shirin H, Hibshoosh H, Kawabata Y, Weinstein IB, Moss SF.p16Ink4a is overexpressed in H pylori-associated gastritis and is correlated with increased epithelial apoptosis. Helicobacter 2003; 8:66-71.
  • 5Kang GH, Shim YH, Jung HY, Kim WH, Ro JY, Rhyu MG.CpG island methylation in premalignant stages of gastric carcinoma. Cancer Res 2001; 61:2847-2851.
  • 6Lee JH, Park SJ, Abraham SC, Seo JS, Nam jH, Choi C,Juhng SW, Rashid A, Hamilton SR, Wu TT. Frequent CpG island methylation in precursor lesions and early gastric adenocarcinomas. Oncogene 2004; 23:4646-4654.
  • 7Fenech M.The role of folic acid and Vitamin B12 in genomic stability of human cells. Mutat Res 2001; 475:57-67.
  • 8Kim YI, Pogribny IP, Salomon RN, Choi SW, Smith DE, James SJ, Mason JB. Exon-specific DNA hypomethylation of P53 gene of rat colon induced by dimethylhydrazine. Modulation by dietary folate. Am J Pathol 1996; 149:1129-1137.
  • 9Ma J, Stamvfer MJ, Giovannucci E, Artigas C, Hunter DJ,Fuchs C, Willett WC, Selhub J, Hennekens CH, Rozen R.Methylenetetrahydrofolate reductase polymorphism, dietary interactions and risk of colorectal cancer. Cancer Res 1997; 57:1098-1102.
  • 10Mayne ST, Risch HA, Dubrow R, Chow WH, Gammon MD,Vaughan TL, Farrow DC, Schoenberg JB, Stanford JL, Ahsan H,West AB, Rotterdam H, Blot WJ, Fraumeni JF. Nutrient intake and risk of subtypes of esophageal and gastric cancer. Cancer Epidemiol Biomarkers Prey 2001; 10:1055-1062.

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  • 1梁增文.胃癌前病变的研究进展[J].广西医学,2005,27(8):1127-1130. 被引量:13
  • 2孙蕾民,姒健敏,樊宇靖.一步法内镜标定活检的实验研究[J].中华消化杂志,2006,26(7):488-489. 被引量:19
  • 3赫捷,陈万青.2012中国肿瘤登记年报[M].北京:军事医学科学出版社,2012:12-25.
  • 4中华医学会消化病学分会.中国慢性胃炎共识意见[J] .中华消化杂志,2007,7(3):46-49.
  • 5Asaka M, Kato M, Sakamoto N. Roadmap to eliminate gastric cancer with Helicobacter pylori eradication and consecutive surveillance in Ja- pan [J]. J Gastroenterol, 2014,49(1) :1 -8.
  • 6Dixon MF, Genta RM, Yardley JH, et al. Classification and grading ofgastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis , Houston 1994 [ J ]. Am J Surg Pathol, 1996, 20:1161-1181.
  • 7Compare D, Rocco A, Nardone G. Long term follow up of patients trea- ted for Helicobacter pylori infection[ J]. World J Gastroenterol,2014, 20(38) :13681 - 13691.
  • 8Jemal A, Bray F, Center MM, et al. Global cancer statistics[J]. CA Cancer J Clin, 2011, 61(2): 69-90. DOI: 10.3322/caac.20107.
  • 9De Dosso S, Sessa C, Saletti P. Adjuvant therapy for colon cancer: present and perspectives[J]. Cancer Treat Rev, 2009, 35(2): 160- 166. DOI: 10.1016/j.ctrv.2008.10.001.
  • 10de Vries AC, van Grieken NC, Looman CW, et al. Gastric cancer risk in patients with premalignant gastric lesions: a nationwide cohort study in the Netherlands[J]. Gastroenterology, 2008, 134(4): 945-952. DOI: 10.1053/j.gastro.2008.01.071.

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