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斑块侵蚀和钙化结节在急性冠状动脉综合征发病中的作用 被引量：1

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摘要 冠状动脉内血栓形成是导致急性冠状动脉综合征（ACS）最常见的原因.而导致血栓形成的最常见机制为斑块破裂（PR）、斑块侵蚀和钙化结节（CN） [1-3].对心脏性猝死（SCD）的患者进行尸检发现,PR最常见[1,4],破裂倾向的斑块有几种组织学特征：（1）薄纤维帽（＜65 μm）;（2）大的脂质池;（3）纤维帽附近巨噬细胞聚集[4-5].同时也发现,很大一部分血栓形成的病变与潜在的斑块破裂并没有什么关系.van der Wal等[61发现在20例SCD患者中有60％发生PR,其余40％仅表现斑块侵蚀.Virmani等[1]对200例SCD患者进行研究发现,只有1/3存在PR,35％的血栓病变并没有PR.与血栓形成的病理相关性最低的是CN.由于缺乏易于识别的诊断形式,斑块侵蚀和CN在ACS患者中的发现率大大降低.本文将从临床表现、病理及影像学检查三方面对斑块侵蚀和CN进行描述,探讨其在ACS发病中的作用.
作者 张林娜 侯静波
机构地区 哈尔滨医科大学附属第二医院心内科
出处 《中国介入心脏病学杂志》 2014年第2期122-124,共3页 Chinese Journal of Interventional Cardiology
关键词 斑块侵蚀 钙化结节 斑块破裂 急性冠状动脉综合征
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献21

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二级参考文献25

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共引文献12

同被引文献14

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中国介入心脏病学杂志
2014年 第2期

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