杜克大学波蒂事件对转化医学研究的启示

Enlightenments of Potti Case at Duke University on Translational Medicine Research

美国杜克大学波蒂事件给复杂疾病的转化研究带来了有益启示:研究诚信基于数据诚信,数据共享之外需要过程透明,要确保医学研究的可重复性应当坚持医学研究的"程序公正",即研究过程合理性。因此需要对转化医学研究进行系统建设,主要包括研究文化和体系建设,即合作平台建设、考评体系建设、学术道德建设、监查体系建设;研究规范与方法学建设,即加强研究者的教育交流和培训,提升研究者对统计学的认识和统计学技能,搭建平台,满足各研究组统计学技术服务需求。

The Potti Case at Duke University has beneficial enlightenments for the translational medicine research, including： research honesty is based on authentic data, procedure needs to be clear, sticking to ＂Procedural Justice＂ namely the rationality of the research in order to ensure the reproducibility. Thus the translational medicine research needs system construction, mainly includes the culture and system construction, namely the cooperation platform construction, evaluation system, academic morality construction, monitoring system and methodology construction, that is, to strengthen the education exchange and training, improve the researchers understanding of statistics and statistical skills, build platform, meet the statistical technical demands of the research teams.