2006～2012年铜绿假单胞菌本院感染调查及耐药监测

Infection distribution and resistant rate of Pseudomonas Aeruginosa from 2006 to 2012

目的 了解铜绿假单胞菌的临床分布及耐药性变迁情况,为临床医师诊断和治疗提供依据。方法 回顾性分析2006年～2012年本院分离的4 699株铜绿假单胞菌的临床分布和耐药情况。结果 所分离出的4 699株铜绿假单胞菌,除亚胺培南、头孢哌酮-舒巴坦外,对其他抗菌药物敏感率较低。结论 铜绿假单胞菌对多种抗菌药物耐药,应加强临床的合理用药并采取积极有效的措施控制耐药菌株在本院的传播。

Objective To understand the clinical distribution and drug resistance of Pseudomonas Aeruginosa and to provide a basis of diagnosis and therapy for clinicians. Methods We retrospectively analyzed the clinical distribution and drug resistance of Pseudomonas Aeruginosa from 4 699 clinical isolates from 2006 to 2012 in our hospital. Results The antibiotic sensitivity rate of 4 699 Pseudomonas Aeruginosa isolates was low, except imipenem and cefoperazone/sulbactam. Conclusion Pseudomonas Aeruginosa is resistant to many antibiotics, so we should strengthen the clinical rational drug use and take effective measures to control the spread of drug-resistant strains in the hospital.