系统应用糖皮质激素治疗白癜风

Treatment of vitiligo with systemic corticosteroids

白癜风是一种常见的色素脱失性皮肤病，发病机制复杂且不完全清楚，治疗方式多样但疗效欠佳。研究表明，系统应用糖皮质激素通过其抗炎、免疫抑制等作用可以控制白癜风的进展、促进皮损复色，其治疗方法包括低剂量每日口服疗法、间歇疗法、冲击疗法，以及联合外用药、光疗、外科治疗等。系统应用糖皮质激素需根据白癜风类型、发展时期选择适宜的治疗方法，才能达到最佳疗效、减少不良反应。

Vitiligo is a kind of common skin disorder characterized by hypopigmentation. The pathogenesis of vitiligo is complex and not yet fully understood. Although many treatment options are available, therapeutic efficacy is unsatisfied. Studies have shown that systemic eortieosteroids can arrest the progression of vitiligo and lead to repigmentation through its anti-inflammatory and immunosuppressive effects. The modalities of cortieosteroid administration include low-dose daily use, intermittent therapy, pulse therapy, with or without combined topical therapy, phototherapy or surgical therapy. The selection of modalities should depend on the type and stage of vitiligo to achieve best therapeutic efficacy and minimize side effects.