摘要
目的 探讨11C-MET PET-CT和MRI图像对脑胶质瘤GTV确定的差异.方法 选取6例经病理证实为胶质瘤患者的术前MRI及11C-MET PET-CT图像,分别由我科5位医师在两种图像资料上勾画GTV,比较两者差异.结果 在MRI11C-MET PET-CT上勾画的GTV体积相似（P=0.917）,GTV变异系数也相似（P =0.600）.勾画的GTV重合度最大为73.0％、最小为51.8％.方差分析显示不同勾画者之间在两种图像资料上勾画的GTV相似（P =0.709）,但PET-CT组GTV最大差值为27.66 cm3,而MRI组的为40.37 cm3.结论 MRI与PET-CT显示的肿瘤边界存在差异,不同勾画者勾画的GTV相似,PET-CT组的GTV最大差值较MRI组的小,11C-MET PET-CT显示GTV较为直观.
Objective To evaluate the difference between MRI and n C-MET PET-CT for gross tumor volume （GTV） delineation in the precision radiotherapy for gliomas. Methods Six patients with a pathologically confirmed diagnosis of gliomas were selected for target delineation. Five physicians in our department were called to delineate the GTV based on the preoperative MRI and n C-MET PET-CT images of these patients. The GTVs based on the two methods were compared. Results There was no significant difference between the GTVs based on MRI and n C-MET PET-CT （P = 0. 917）, and their coefficients of variation were also similar （ P = 0. 600）. The coincidences of GTVs were different among the patients, with a maximum value of 73.0% and a minimum value of 51.8%. GTV showed no significant difference when defined by different physicians on MRI and PET-CT （P = 0. 709） ; the biggest difference was 27. 66 cm3 on PET-CT and 40. 37 cm3 on MRI. Conclusions The boundaries of gliomas defined on MRI and PET-CT are different. The GTVs delineated by different physicians on MRI and PET-CT are similar, and the biggest difference on PET-CT is smaller than that on MRI, which suggests that 11C-MET PET-CT is a more direct way for displaying GTV.
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
2014年第2期143-146,共4页
Chinese Journal of Radiation Oncology
基金
安徽省科技攻关计划项目（07010302202）
