降钙素原、C反应蛋白在重症细菌感染诊疗中的应用被引量：2

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摘要目的比较降钙素原（PCT）和C反应蛋白（CRP）在重症细菌感染诊断和治疗中的应用.方法将重症监护病房（ICU）的114例患者分为脓毒症组（52例）、非脓毒症组（62例）,进行PCT、CRP检测,同时与62例自身免疫病患者（自身免疫组）进行比较.脓毒症组进行治疗前及治疗5天后PCT、CRP动态监测.结果与非脓毒症组及自身免疫组比较,脓毒症组PCT明显升高（P＜0.01）;非脓毒症组和自身免疫组PCT无明显升高,差异无统计学意义（P＞0.05）.脓毒症组、非脓毒症组及自身免疫组CRP均明显升高,但3组间差异无统计学意义（P＞0.05）.与治疗前比较,脓毒症组经抗生素治疗5天后PCT、CRP明显降低（P＜0.01）.PCT比CRP 用于观察重症细菌感染抗菌药物疗效敏感性更高.结论 PCT是指导重症细菌感染诊疗的可靠指标,其特异性明显高于CRP.

作者金玉张颖

机构地区徐州医学院附属医院检验科

出处《徐州医学院学报》 CAS 2014年第1期57-58,共2页 Acta Academiae Medicinae Xuzhou

关键词降钙素原 C反应蛋白重症细菌感染

分类号 R446.62 [医药卫生—诊断学]

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