肝硬变腹水中医证型与血清-腹水白蛋白梯度相关性研究

Study of Relativity Between TCM Syndromes of Ascites due to Cirrhosis and Serum Ascites Albumin Gradient( SAAG)

目的:探讨肝硬变腹水中医辨证分型与血清-腹水白蛋白梯度(SAAG)之间的相关性。方法:将256例肝硬变腹水患者进行中医辨证分型,并进行SAAG检测,通过统计学方法,探讨二者之间的相关性。结果:气滞湿阻证SAAG值较低,与其他证型比较,差异具有统计学意义(P<0.05);湿热蕴结证与寒湿困脾证SAAG值接近,差异无统计学意义(P>0.05);肝脾血瘀证与脾肾阳虚证SAAG值接近,差异无统计学意义(P>0.05);湿热蕴结证与肝脾血瘀证、脾肾阳虚证比较,SAAG值较高,差异有统计学意义(P<0.05);寒湿困脾证与肝脾血瘀证、脾肾阳虚证比较,SAAG值较高,差异有统计学意义(P<0.05);肝肾阴虚证与其他证型比较,SAAG值较高,差异有统计学意义(P<0.05)。结论:肝硬变腹水中医证型与SAAG存在相关性。

Objective： To explore the relativity between TCM syndromes of ascites due to cirrhosis and serum ascites albumin gradient （ SAAG） . Methods ：256 patients with ascites due to cirrhosis were divided into six groups according to TCM syndromes, and SAAG was measured by using statistical method to explore the relativity between them. Results： Compared with other TCM syndromes, SAAG of patients with cirrhosis ascites with syndrome of blockade of dampness due to qi stagnationthe was a little low, and the difference had statistical significance（ P 〈 0.05）. SAAG of accumulation of damp - heat syndrome was near equal to that of syndrome of cold - dampness disturbing spleen, and the difference had no statistical significance （ P 〉 O. 05）. SAAG of syndrome of liver - spleen blood stasis was near equal to that of syndrome of spleen - kidney yang deficiency, and the difference had no statistical significance（ P 〉 0.05）. Compared with syndrome of liver - spleen blood stasis and syndrome of spleen - kidney yang deficiency, SAAG of accumulation of damp - heat syndrome was relatively high, and the difference had statistical significance （P 〈 0.05） ; and SAAG of syndrome of cold - dampness disturbing spleen was relatively high, and the difference had statistical significance（ P 〈 O. 05） . Compared with other syndromes, SAAG of syndrome of liver - kidney yin deficiency was relatively high, and the difference had statistical significance （ P 〈 O. 05）. Conclusion： There is relativity between TCM syndromes of ascites due to cirrhosis and serum ascites albumin gradient （ SAAG）.