血管平滑肌细胞凋亡在血管再狭窄中作用的研究进展

Role of vascular smooth muscle cell apoptosis in vascular restenosis

血管平滑肌细胞构成新生内膜增生的重要部分,且在血管腔内治疗术后再狭窄的心血管疾病的发生和发展中具有重要作用。血管平滑肌细胞凋亡能有效抑制血管球囊损伤和血管旁路移植术后新生内膜增生,从而可为血管术后再狭窄提供治疗手段。

Vascular smooth muscle cell is an important cell component of neointimal hyperplasia and plays a crucial role in the development and progression of vascular restenosis, which usually results from balloon angioplas~ stenting and other vascular diseases. Vascular smooth muscle cell apoptosis can effectively reduce vascular restenosis and in turn to inhibit neointimal hyperplasia, which may provide a way to treat vascular restenosis.