不同浓度臭氧腰椎旁间隙注射治疗腰椎间盘突出症的临床观察

Clinical Observation of Lumbar Parapharyngeal Space Injection of Different Concentrations of Ozone in Patients with Lumbar Disc Herniation

目的探讨不同浓度臭氧椎旁间隙注射在腰椎间盘突出症患者中的疗效。方法132例腰椎间盘突出症患者随机均分为A、B、C三组。每组44例，均给予臭氧腰椎旁间隙注射治疗，A组浓度为25μg／ml，B组为40μg／ml，C组为60／,g／ml，注射量均为10～15ml，对比i组患者治疗效果。结果B组患者术后3个月、6个月及12个月时的优良率均显著高于A、C丽组（P〈0．01）；三组患者治疗后视觉模拟评分法（visualanaloguescore，VAS）均显著低于治疗前（P〈0．01）；且B组显著低于A、C两组（P〈0．01或P〈0．05）。结论臭氧腰椎旁间隙注射治疗腰椎间盘突出症疗效确切，安全可靠，但40μg／ml浓度的臭氧对于该病的治疗效果更佳。

Objective To study the clinical effects of lumbar parapharyngeal space injection of different eoncentra tions of ozone in patients with lumbar disc herniation （LDH）. Methods A total of 132 LDH patients were randomly di- vided into group A （n = 44）, group I3 （n = 44）, and group C （n = 44）. All the patients were treated with lumbar parapha- ryngeal space injection of 10-15 ml ozone with the concentrations as 25μg/ml in group A, 40 μg/ml in group B, and 60μg/ml in group C. The clinical effects were contrasted between the three groups. Results The excellent rate in group B was significantly higher than that in group A and C 3, 6, and 12 months after the treatment （P〈0.01）. Visual ana logue scores （VASs） in all the groups were significantly lower than before （P〈0. 01）, and significantly lower in group B after the treatment than those in the other two groups （P〈0. 01 or 1）. （15）. Conclusion Lumbar parapharyngeal space in- jection of ozone has exact treatment effects in LDH patients, especially in the concentration of 40μg/ml.