脑卒中患者中检测N-末端脑钠肽前体、D二聚体、超敏C反应蛋白的临床价值

The Clinical Value of Detected in N-Terminal Pro-Brain Natriuretic Peptide,D-dimer,High-sensitivity C-Reactive Protein with Stroke Patients

目的探讨在脑卒中患者中检测N-末端脑钠肽前体(NT-proBNP)、D二聚体(D-D)、超敏C反应蛋白(hs-CRP)的临床价值。方法选择101例脑卒中住院患者和100例健康对照组分别测定NT-proBNP、D-D、hs-CRP并分别进行比较。结果 NT-proBNP、D-D和hs-CRP在梗死1组、梗死2组、梗死3组与对照组比较或两两比较中均有显著差异(P<0.05);在急性期、亚急性期、慢性期与对照组比较或两两比较中也均有显著差异(P<0.05)。结论 NTproBNP、D-D和hs-CRP可作为预测脑卒中病程的三项指标,三者的联合检测可作为脑梗死面积大小和病程进展情况的参考。

Objective To discuss clinical value of detected in N-terminal pro-brain natriuretic pep- tide,d-dimer,high-sensitivity c-reactive protein with stroke patients. Method We compare 101 stroke pa- tients and 100 health people by detecting NT-pro BNP,D-Dimer and hs-CRP. Result Compared with control group, there is significant differences of N- terminal pro- brain natriuretic peptide, d- dimer, high- sensitivity c- reactive protein in the first infarct group, second infarct group and third infarct group. And compared with con- trol group, there is also significant differences in acute, subacute and chronic period. Conclusion N-terminal pro-brain natriuretic peptide, d-dimer, high-sensitivity c-reactive protein can be used as three indicators in predicting the progress of stroke.