孤独症谱系障碍患者食物不耐受的研究

The Food Intolerance in Patients with Autism Spectrum Disorder

目的探讨孤独症谱系障碍(ASD)患者和食物不耐受(食物敏感)二者之间的关系。方法对30例ASD患者、30例精神发育迟滞的患者和30例正常对照组进行食物不耐受的检测。结果 ASD组食物不耐受的阳性发生率为46.7%,显著高于精神发育迟滞组的16.7%(χ2=4.08,P<0.05)和正常组的13.3%(χ2=4.83,P<0.05);食物不耐受阳性的14例ASD患者的孤独症行为量表(ABC)得分为较阴性者的显著为高(t=4.23,P<0.01)。结论 ASD与食物不耐受有关,食物不耐受阳性的ASD患者症状较严重。

Objective To explore the relationship between patients with Autism Spectrum Disorder（ASD） and food intolerance（food sensitivity）. Methods The index of food intolerance was detected for patients with ASD and mental retardation （ n = 30）, meanwhile the normal group was detected （ n = 30）. Results The incidence of food intolerance in ASD group was 46.7 %, which was significantly higher than 16.7 % in mental retardation group （X2 = 4.08, P 〈 0. 05 ） and 13.3 % in normal group（χ^2 =4. 83, P 〈 0. 05 ）. The score of autism behavior checklist（ABC） in patients with food intolerance for ASD （ n = 14） was （75.3 - 9.4）, which was higher than negative patients （ t = 4. 23, P 〈 0. 01 ）. Conclusion ASD is related to food intolerance. Moreover, the symptom of ASD in patients with food intolerance is more serious.