医院感染鲍氏不动杆菌的分布特点及耐药性分析

Analysis of distribution and durg resistance in Acinetobacter baumannii of nosocomial infections

目的了解医院感染鲍氏不动杆菌的分布特点以及耐药性,为临床治疗鲍氏不动杆菌感染提供参考依据。方法收集医院2010年1月-2011年12月临床分离的鲍氏不动杆菌,采用K-B法进行药物敏感试验,利用SPSSB进行多因素logistic回归统计分析。结果 340株鲍氏不动杆菌主要分布在呼吸内科占17.94%、神经内科占17.94%,来源以痰为主占82.94%;对头孢哌酮/舒巴坦、头孢吡肟及多黏菌素B耐药率较低,分别为3.61%、3.61%及5.44%。结论应不断提高医务人员对鲍氏不动杆菌医院感染流行和耐药性趋势的认识,积极控制易感因素。

OBJECTIVE To explore the distribution characteristics and related factors of Acinetobacter baumannii nosocomial infections so as to Provide basis for clinical treatment of Acinetobacter baumannii infection. METHODS Clinical isolates of A. baumannii in our hospital were collected from January 2010 to December 2011; K-B method for drug susceptibility testing was used. Used SPSS to conduct the logistic regression analysis. RESULTS Of 340 A. baumannii , 17.94% and 17. 94 were mainly distributed in Respiratory Medicine. and department of Neurology; source sputum was mainly 82. 94% of specimen. The resistance rate to cefoperazone/sulbactam was 3.61%, polymyxin B 5. 44 %. CONCLUSION It is better to continue to improve the understanding of the Acinetobacter nosocomial infection prevalence and resistance trends among medical staff, which would actively control the risk factors.