偏倚风险评估工具在针刺Cochrane系统评价中的应用

Application of Risk of Bias Tool in Cochrane Systematic Reviews on Acupuncture

目的客观评价偏倚风险评估工具在针刺Cochrane系统评价（CSR）的应用情况。方法全面检索Cochrane系统评价数据库（2011年第12期），查找有关针刺的CSR。由2位研究者根据纳入与排除标准独立筛选文献、提取资料，然后进行统计分析。结果共纳入41个CSR。其中有19个为更新的系统评价，33个发表于2009～2011年间；60．98％报告采用了CochraneHandbook评估纳入研究偏倚风险／方法学质量；所有研究均评价了随机序列、分配隐藏及盲法信息，但未完整报告施盲对象；54．55％的研究分别报告了选择性报告偏倚和其他偏倚来源。结论大多数CSR选择使用CochraneHandbook推荐的偏倚风险评估工具评估纳入研究的偏倚风险，但依然有评估条目报告不完整的问题存在。

Objective To evaluate whether and to what extent the new risk of bias （ROB） tool has been used in Cochrane systematic reviews （CSRs） on acupuncture. Methods We searched the Cochrane Database of Systematic Review （CDSR） in issue 12, 2011. Two reviewers independently selected CSRs which primarily focused on acupuncture and moxibustion. Then the data involving in essential information, the information about ROB （sequence generation, allocation concealment, blindness, incomplete outcome data, selective reporting and other potential sources of bias） and GRADE were extracted and statistically analyzed. Results In total, 41CSRs were identified, of which 19 CSRs were updated reviews. Thirty-three were published between 2009 and 2011.60.98% reviews used the Cochrane Handbook as their ROB assessment tool. Most CSRs gave information about sequence generation, allocation concealment, blindness, and incomplete outcome data, however, half of them （54.55%, 8/69） showed selective reporting or other potential sources of bias. Conclusion ＂Risk of bias＂ tools have been used in most CSRs on acupuncture since 2009. However, the lack of evaluation items still remains.