2型糖尿病早期视网膜病变选择性药物治疗的临床研究

The effects of different drug programs in the treatment of early diabetic retinopathy

目的探讨2型糖尿病早期视网膜病变的药物治疗方案。方法以我院收治的90例2型糖尿病早期视网膜病变患者为研究对象,随机分为A、B、C三组。A组患者使用利多卡因治疗,B组患者使用胰激肽原酶治疗,C组患者则A、B两组方案联合应用。比较三组患者临床治疗效果、血流动力学指标及视网膜神经纤维层厚度之间的差异。结果 C组治疗效果优于单独用药的A、B组,血流动力学指标低于A、B组,视网膜神经层厚度小于A、B两组,差异均有统计学意义(P<0.05)。结论联合使用利多卡因和胰激肽原酶可以更有效的治疗糖尿病早期视网膜病变,可提高临床治疗效果,改善患者血流动力学指标,降低患者神经纤维层厚度。

Objective To investigate the effect of different drug programs in the treatment of early diabetic retinopathy. Methods A total of 90 patients with early diabetic retinopathy were divided into group A,group B and group C. The lidocaine was used in group A. The pancreatic kininogenase was used in the B group. The combination lidocaine and pancreatic kininogenase were used in the C group. The clinical effect, hemodynamic indexes and the retinal nerve fiber layer thickness were compared among the three groups. Results The clinical effect and hemodynamic indexes of the group C were better than those in group A,B, and retinal nerve fiber layer thickness in group C was thinner than that in group A,B. Conclusion It can get a satisfaction effect to combined application lidocaine and pancreatic kinino- genase in the treatment of early diabetic retinopathy, with better clinical effect and hemodynamic indexes,and thinne retinal nerve fibel＂ layer.