摘要
目的探讨肺炎支原体感染儿童血清免疫相关指标的变化及临床意义。方法选择肺炎支原体感染患儿30例作为肺炎支原体感染组,健康儿童30例作为对照组。检测两组血清免疫指标水平,分析两组之间的差异。结果肺炎支原体组IgG水平低于对照组(P<0.05),IgM、IgE、IL-18、嗜酸性粒细胞水平高于对照组(P<0.05或者P<0.01)。肺炎支原体感染患儿血清IL-18水平与IgE呈正相关(r=0.401,P<0.05)。结论肺炎支原体感染患儿血清IL-18、IgE、IgM和外周血管嗜酸性粒细胞升高,IL-18与IgE呈正相关。
Objective To discuss clinical significance and change of serum immune related indicators in children with mycoplasma pneumoniae infection. Methods Selected 30 cases with mycoplasma pneumoniae infection as MP group, and 30 healthy as control group. Serum immune related indicators were detected and compared. Results The IgG of MP group was lower than control group （P〈0.05）,IgM,IgE,IL-18,EOS of MP group were higher than control group（P〈0.05 or P〈0.01）. IL-18 showed positive correlation with IgE（r=0.401 ,P〈0.05）. Conclusion Levels of IL-18, IgE, IgM, EOS of MP increase, and IL-18 show positive correlation with IgE.
出处
《中国现代医生》
2014年第8期104-107,共4页
China Modern Doctor
基金
国家自然科学基金(81070004/H0104)
