82例小脑性眩晕抗焦虑治疗疗效分析

The clinical effects of anxiolytic therapy in the treatment of cerebellar vertigo: a study of 82 cases

目的探讨小脑性眩晕伴焦虑的原因及其抗焦虑治疗的疗效。方法自2009年1月开始,对三家医院收治的小脑性眩晕伴焦虑患者82例随机分为治疗组和对照组,治疗组进行常规治疗+氟哌塞顿美利曲辛联合度洛西汀抗焦虑治疗,对照组进行常规治疗。在入院时及治疗2、4、8周末给予眩晕量表和哈密尔顿焦虑量表(HAMA)评分。结果治疗组与对照组在入院时眩晕量表及HAMA量表评分两者无显著性差异(均P>0.05)。治疗后,治疗组在2周末、4周末和8周末眩晕量表及HAMA量表评分较对照组明显偏低(均P<0.05)。对照组8周末时眩晕量表评分较4周末时反而上升,差异有极显著性意义(P<0.01)。结论小脑性眩晕伴焦虑患者,积极进行抗焦虑治疗有益于改善患者焦虑及眩晕症状。

Objective To explore the causes of anxiety in cerebellum vertigo and evaluate the efficacy of anxiolytic therapy.Method Since January, 2008, patients of cerebellar vertigo with anxiety were randomly divided into an experimental group and a control group in three hospitals .The experimental group were treated with routine therapy plus anxiolytic therapy with droperidol seton melitracen and duloxetine , while the control group were administered with conventional treatment .The patients received evaluation with Dizziness Scale and Hamilton Anxiety Scale （ HAMA） on admission and 2,4,8 weeks after treatment.Findings At the time of admission, no significant differences were found in the vertigo and HAMA scale scores between the two groups （ P〉0.05）.After treatment, the experimental group scored significantly lower than the control group in the vertigo and HAMA scale at the end of 2,4,8 weeks（P〈0.05）.The control group for 8 weeks at the vertigo score over 4 weeks at the rise.The difference was very significant （P〈0.01）.Conclusion Anxiolytic therapy was effective for the treatment of cerebellar vertigo with anxiety .