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血清胱抑素C对2型糖尿病患者肾脏损伤早期预警能力的研究 被引量：4

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摘要 目的探讨血清胱抑素C(Cys C)检测能否作为糖尿病患者糖尿病肾病早期检测指标。方法选择血压小于130/80mm Hg,尿清蛋白大于或等于30mg/gCr且小于300mg/gCr,肾小球滤过率(eGFR)>90mL/min的患者共135例。比较血清Cys C、尿清蛋白和eGFR之间的相关性,计算血清Cys C在该患者群的阳性率。结果该患者群中血清Cys C高于正常上限的占5.2%;低于正常下限的占3.7%。血清Cys C与尿清蛋白和eGFR结果间不存在相关性,R2分别为0.002 5和0.016 0。结论血清Cys C的诊断灵敏度不足以提示糖尿病患者的早期肾脏损伤。
作者 沈雄文 李静云 孙关忠 胡云华 裘敏丽
机构地区 中国人民解放军第一一七医院检验科
出处 《国际检验医学杂志》 CAS 2014年第5期626-627,共2页 International Journal of Laboratory Medicine
关键词 糖尿病 半胱氨酸蛋白酶抑制剂 肾损伤
分类号 R587.1 [医药卫生—内分泌] R692 [医药卫生—泌尿科学]
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参考文献12

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二级参考文献11

共引文献26

同被引文献26

  • 1张新春,陈涛.尿微量白蛋白测定在高血压早期肾损害诊断中的临床应用[J].检验医学与临床,2006,3(1):25-26. 被引量：13
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  • 10梁宁,郑青,陈夏明.原发性高血压肾病患者血清胱抑素C和尿微量白蛋白检测的临床意义[J].标记免疫分析与临床,2009,16(6):342-343. 被引量：9

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国际检验医学杂志
2014年 第5期

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